五月激情综合美女久久,安徽妇搡BBBB搡BBBB袄爱直播,国产做爰XXXⅩ高潮视频12p,女人野外做爰A片妓女潘金莲,蜜桃又粗又爽成人www网站

Total tau (t-tau) kit

Tau protein is a scaffold protein in the microtubule associated protein family. Tau proteins are mainly enriched, in normal neurons, around neuronal axons, regulating, maintaining microtubule stability, and assisting in neuronal axon transport. It supports the neuronal cytoskeleton and microtubule stability by promoting tubular polymerization. It is encoded by the microtubule associated protein tau (MAPT) gene, an unfolded protein that undergoes PTM, which alters the structure and affects their function, interaction, and aggregation. PTMs such as phosphorylation, methylation and acetylation regulate the normal function of Tau. Post-translational modifications (PTMs) of Tau proteins have been found to be an important way to regulate their protein structure and function.

Aβ 40 kit

Aβ 40 is a protein fragment consisting of 40 amino acid residues. It is the product of enzymatic cleavage of amyloid precursor protein (APP) between valine 711 and isoleucine 712 by protein hydrolase. It contains the most abundant amyloid peptide in cerebrospinal fluid (CSF) and plasma (10- to 20-fold higher than that in Aβ42).

Aβ 42 kit

Aβ 42 can activate microglia and complement, release cytokines, free radicals, NO and toxins during agglutination, induce inflammation, affect microtubule stability, contribute to the abnormal phosphorylation of microtubule-associated protein Tau, and activate apoptotic signalling pathway, resulting in neuronal apoptosis and necrosis. It is the main form of neuronal loss in AD patients.


P-tau181 kit

P-tau 181, the phosphorylation of Tau protein at threonine 181, is a highly specific pathological marker for AD, since it is normal in patients with other dementias (i.e., dementias other than AD). So P-tau181 can be used as a highly specific biomarker for AD. As an important blood biomarker for AD, P-tau181 is less invasive and more readily available than markers based on CSF, where it is expected to be used for early and accurate detection of AD in a large population.


P-tau217 kit

P-tau 217 is the phosphorylation of Tau protein at threonine 217. Multiple studies have demonstrated that the burden of nerve tangles at the 217 site is highly correlated with disease severity compared to P-tau181. P-tau217 in blood samples can effectively differentiate AD from other neurodegenerative disorders, thus P-tau217 can be used as a highly specific biomarker for AD.


P-tau231 kit

P-tau 231, the phosphorylation of Tau protein at threonine 231, is a promising new biomarker for AD pathology.

NF-L kit

NF-L (neurofilament-light), as a component of nerve fibre skeleton protein, is one of the components of neurofilaments (NFs), and plays an important role in maintaining axonal morphology and nerve transmission. After nerve axonal injury, the assembly and transportation of NFs cannot be completed normally, resulting in axonal lesions, mainly manifested as reduced neuronal axon diameter and impaired nerve conduction. NFs are elevated in the cerebrospinal fluid of many neurological diseases, such as multiple sclerosis, amyotrophic lateral sclerosis, vascular dementia, traumatic brain injury, and Alzheimer's disease. So, NFs are the biomarkers of neural axonal injury. The detection of neurofilament protein light chain can be used to determine neurodegenerative behaviours in AD.


GFAP kit

GFAP is the English abbreviation for glial fibrillary acidic protein and it is a marker of astrocyte activation. Glial fibrillary acidic protein. GFAP is an intermediate filament III protein that exists in monomeric form. Astrocyte proliferation is often accompanied by increased expression of GFAP. Therefore, GFAP can serve as a biomarker for astrocyte proliferation following central nervous system injury.


α- Synuclein kit

α- Synuclein is the most critical protein in the pathogenesis of Parkinson's disease and a major structural component of Lewy bodies. Aggregation of a-Synuclein is closely associated with the formation of the Lewy body and the death of dopaminergic neurons

S-100β kit

S-100β protein is a calcium-binding protein secreted by glial cells. Approximately 96% of S-100β protein is expressed in astrocytes in the brain, which can nourish the nerves, and also influence the growth, proliferation and differentiation of glial cells, maintain calcium homeostasis in the brain, promote brain development, improving learning and memory.

Brain-derived neurotrophic factor (BDNF)

BDNF is the most important neurotrophic factor in the brain. It is a generic term for protein molecules maintaining the survival of neurons, encouraging differentiation (synaptic elongation and expression of neurotransmitter synthase, etc.), promoting maturation, and regulating function. BDNF is secreted mainly by astrocytes and is one of the most widely distributed and studied neurotrophic factors in mammals. Its prominent function is to regulate neuronal development and synapse formation.

Human APOE gene ε2/ε3/ε4 genotyping kit

Human APOE gene consists of three alleles based on two SNP loci (rs429358 and rs7412): ε2, ε3 and ε4. 6 genotypes of APOE gene: ε2/ε2, ε2/ε3, ε2/ε4, ε3/ε3, ε3/ε4, ε4/ε4. The Epsilon 3 allele is the wild type, playing an important role in the normal physiological function of the body; The variant E4 has been implicated in a high prevalence of Alzheimer's disease, depression, and cardio-tubular diseases; Variant E2 is a protective factor against Alzheimer's disease, stroke, cerebral infarction, and coronary heart disease.


亚洲一区免费在线观看 | 成年免费视频黄网站在线观看 | 欧美性XX兔费观看 | 女生高潮喷水抽搐视频 | 欧美AAAAA一二一二区区 | 国产精品昆明久久久综合888 | 69人人人人人人人人人 | A片丰满奶水的护士 | 成人片黄网站久久久免费 | 91人人妻人人澡人人爽人人精品99 | ZZJJ国产精品一区二区 | 无码人妻一区二区三区密桃手机版 | 媚黑极品魔都绿帽人妻找黑人 | 国产高清一级AV片 | 成人3D动漫一区二区三区91 | A片人人澡C片人人人妻蜜臀动图 | 精品久久人人爽人人玩人人妻 | 又粗又大又黄免费视频 | 精品国产AV无码一区二区 | 乱伦文学亚洲色图亚洲无码 | 午夜成人电影免费观看 | 国产乱国产乱老熟300 | 女人自慰喷白浆A片免费下载 | 无码人妻一区二区三区潮湿 | 色婷婷一区二区三区久久午夜成人 | 国产高清无马在线观看 | 20岁黄色一级片 | 黄色视频免费观看网站 | 欧亚乱熟女一区二区在线 | 夜夜躁精品AAAAXXXX | 奶大灬大灬大灬硬灬爽灬无码视频 | 红桃在线无码精品国产 | 黄色视频AAA级毛片 欧美必出精品在线观看 | 亚洲一级视频在线观看 | 91在线无码精品秘 软件网站 | 丰满少妇人妻一区二区三区 | 初中麻豆啪啪啪黑丝免费 | 四川BBB搡BBB爽爽爽 | 亚洲AV无码久久蜜桃杨思敏 | 国产日韩成人精品一区二区 | 美女裸体视频网站软件 |